Head to Head
| Mexico - Liga MX | 2018/11/12 00:00 | Santos Laguna v Club America | D | 1-1 |
| Mexico - Liga MX | 2018/05/14 00:00 | Club America v Santos Laguna | D | 2-2 |
| Mexico - Liga MX | 2018/05/11 00:30 | Santos Laguna v Club America | L | 4-1 |
| Mexico - Liga MX | 2018/04/29 02:00 | Club America v Santos Laguna | W | 1-0 |
| Mexico - Liga MX | 2017/11/20 00:30 | Santos Laguna v Club America | W | 0-1 |
| Europa - Vriendschappelijke wedstrijden | 2017/07/06 01:30 | Club America v Santos Laguna | W | 3-2 |
| Mexico - Liga MX | 2017/04/24 00:00 | Santos Laguna v Club America | L | 2-1 |
| Mexico - Beker | 2017/03/02 02:30 | Santos Laguna v Club America | L | 2-1 |
Home History
| Mexico - Liga MX | 2018/12/17 00:30 | Cruz Azul v Club America | W | 0-2 |
| Mexico - Liga MX | 2018/12/14 02:30 | Club America v Cruz Azul | D | 0-0 |
| Mexico - Liga MX | 2018/12/10 00:45 | Club America v Unam Pumas | W | 6-1 |
| Mexico - Liga MX | 2018/12/03 00:30 | Club America v Toluca | W | 3-2 |
| Mexico - Liga MX | 2018/11/30 01:00 | Toluca v Club America | D | 2-2 |
| Mexico - Liga MX | 2018/11/25 01:00 | Club America v Veracruz | W | 4-1 |
| Mexico - Liga MX | 2018/11/12 00:00 | Santos Laguna v Club America | D | 1-1 |
| Mexico - Liga MX | 2018/11/04 01:00 | Club America v Toluca | D | 1-1 |
Away History
| Mexico - Liga MX | 2018/12/02 03:00 | Santos Laguna v Monterrey | L | 0-2 |
| Mexico - Liga MX | 2018/11/29 03:06 | Monterrey v Santos Laguna | L | 1-0 |
| Mexico - Liga MX | 2018/11/25 18:00 | Unam Pumas v Santos Laguna | D | 1-1 |
| Mexico - Liga MX | 2018/11/12 00:00 | Santos Laguna v Club America | D | 1-1 |
| Mexico - Liga MX | 2018/11/04 22:00 | Queretaro v Santos Laguna | L | 2-1 |
| Mexico - Liga MX | 2018/10/27 00:00 | Santos Laguna v Monterrey | W | 1-0 |
| Mexico - Liga MX | 2018/10/21 00:00 | Pachuca v Santos Laguna | D | 1-1 |
| Mexico - Liga MX | 2018/10/06 00:00 | Santos Laguna v Atlas | W | 3-1 |