Stadium: Estadio Manuel Murillo Toro Round: 7
| Colombia - Liga - Dames | 2022/04/07 20:00 | Deportes Tolima - Dames v Fortaleza FC - Dames | D | 1-1 |
| Colombia - Liga - Dames | 2022/04/02 18:00 | Independiente Santa Fe - Dames v Deportes Tolima - Dames | L | 3-0 |
| Colombia - Liga - Dames | 2022/03/30 21:00 | Deportes Tolima - Dames v Deportivo Cali - Dames | L | 0-2 |
| Colombia - Liga - Dames | 2022/03/27 20:30 | Atletico Huila - Dames v Deportes Tolima - Dames | D | 1-1 |
| Colombia - Liga - Dames | 2022/03/23 20:00 | Deportes Tolima - Dames v Junior - Dames | D | 0-0 |
| Colombia - Liga - Dames | 2022/03/15 20:00 | Orsomarso - Dames v Deportes Tolima - Dames | L | 4-2 |
| Colombia - Liga - Dames | 2022/03/10 20:00 | Deportes Tolima - Dames v Atletico Bucaramanga - Dames | D | 0-0 |
| Colombia - Liga - Dames | 2022/03/07 20:00 | Atletico Nacional Medellin - Dames v Deportes Tolima - Dames | W | 1-3 |
| Colombia - Liga - Dames | 2022/04/07 23:00 | Junior - Dames v Deportivo Pereira - Dames | L | 2-1 |
| Colombia - Liga - Dames | 2022/04/03 00:00 | Deportivo Pereira - Dames v Millonarios - Dames | L | 0-1 |
| Colombia - Liga - Dames | 2022/03/30 19:00 | La Equidad - Dames v Deportivo Pereira - Dames | W | 0-1 |
| Colombia - Liga - Dames | 2022/03/26 22:00 | Deportivo Pereira - Dames v America de Cali - Dames | D | 1-1 |
| Colombia - Liga - Dames | 2022/03/15 20:00 | Deportivo Pereira - Dames v CD Real Santander - Dames | W | 2-1 |
| Colombia - Liga - Dames | 2022/03/09 20:00 | Internacional FC de Palmira - Dames v Deportivo Pereira - Dames | W | 0-1 |
| Colombia - Liga - Dames | 2022/03/05 19:00 | Deportivo Pereira - Dames v Llaneros - Dames | D | 1-1 |
| Colombia - Liga - Dames | 2022/03/02 20:00 | Independiente Medellin - Dames v Deportivo Pereira - Dames | L | 2-1 |