Stadium: Rose Bowl
Referee: Simon Hinks
| The Hundred | 2021/08/01 13:30 | London Spirit - Dames v Southern Brave - Dames | 93-97 |
| The Hundred | 2021/08/21 14:00 | Southern Brave - Dames v Oval Invincibles - Dames | 73-121 |
| The Hundred | 2021/08/16 14:30 | Southern Brave - Dames v Oval Invincibles - Dames | 115-85 |
| The Hundred | 2021/08/11 14:00 | Southern Brave - Dames v Welsh Fire - Dames | 166-127 |
| The Hundred | 2021/08/07 14:30 | Southern Brave - Dames v Northern Superchargers - Dames | 89-76 |
| The Hundred | 2021/08/05 14:30 | Manchester Originals - Dames v Southern Brave - Dames | 97-123 |
| The Hundred | 2021/08/01 13:30 | London Spirit - Dames v Southern Brave - Dames | 93-97 |
| The Hundred | 2021/07/30 14:00 | Southern Brave - Dames v Birmingham Phoenix - Dames | 141-140 |
| The Hundred | 2021/07/27 14:00 | Welsh Fire - Dames v Southern Brave - Dames | 110-112 |
| The Hundred | 2021/08/18 14:00 | Welsh Fire - Dames v London Spirit - Dames | 95-96 |
| The Hundred | 2021/08/14 14:30 | Oval Invincibles - Dames v London Spirit - Dames | 107-103 |
| The Hundred | 2021/08/10 14:00 | Manchester Originals - Dames v London Spirit - Dames | 127-131 |
| The Hundred | 2021/08/03 14:00 | London Spirit - Dames v Northern Superchargers - Dames | 129-126 |
| The Hundred | 2021/08/01 13:30 | London Spirit - Dames v Southern Brave - Dames | 93-97 |
| The Hundred | 2021/07/29 14:00 | London Spirit - Dames v Trent Rockets - Dames | 133-151 |
| The Hundred | 2021/07/25 10:00 | London Spirit - Dames v Oval Invincibles - Dames | 117-132 |
| The Hundred | 2021/07/23 14:00 | Birmingham Phoenix - Dames v London Spirit - Dames | 128-132 |