| Uruguay - Reserve League | 2022/05/10 18:00 | Defensor Sporting - Reserves v Cerrito - Reserves | L | 3-1 |
| Uruguay - Reserve League | 2022/11/21 17:00 | Cerrito - Reserves v Albion FC - Reserves | L | 0-4 |
| Uruguay - Reserve League | 2022/11/14 19:00 | Torque - Reserves v Cerrito - Reserves | D | 1-1 |
| Uruguay - Reserve League | 2022/11/04 18:00 | Cerrito - Reserves v Penarol - Reserves | L | 1-5 |
| Uruguay - Reserve League | 2022/10/24 18:00 | Cerrito - Reserves v Atletico Fenix - Reserves | D | 1-1 |
| Uruguay - Reserve League | 2022/09/27 18:00 | Cerrito - Reserves v Cerro Largo - Reserves | D | 1-1 |
| Uruguay - Reserve League | 2022/09/06 18:00 | Rentistas - Reserves v Cerrito - Reserves | W | 1-2 |
| Uruguay - Reserve League | 2022/08/30 13:00 | Cerrito - Reserves v Atletico River Plate Reserves | W | 2-1 |
| Uruguay - Reserve League | 2022/08/23 18:00 | Deportivo Maldonado - Reserves v Cerrito - Reserves | L | 3-0 |
| Uruguay - Reserve League | 2022/11/21 19:00 | Nacional de Montevideo - Reserves v Defensor Sporting - Reserves | L | 3-1 |
| Uruguay - Reserve League | 2022/11/14 12:30 | Defensor Sporting - Reserves v Albion FC - Reserves | W | 5-1 |
| Uruguay - Reserve League | 2022/11/04 13:00 | Atletico Fenix - Reserves v Defensor Sporting - Reserves | L | 5-0 |
| Uruguay - Reserve League | 2022/10/25 18:00 | Defensor Sporting - Reserves v Cerro Largo - Reserves | W | 4-0 |
| Uruguay - Reserve League | 2022/10/11 13:00 | Atletico River Plate Reserves v Defensor Sporting - Reserves | D | 0-0 |
| Uruguay - Reserve League | 2022/09/27 13:00 | Defensor Sporting - Reserves v Boston River - Reserves | L | 2-3 |
| Uruguay - Reserve League | 2022/09/12 18:00 | Defensor Sporting - Reserves v Penarol - Reserves | W | 2-1 |
| Uruguay - Reserve League | 2022/09/06 14:11 | Plaza Colonia - Reserves v Defensor Sporting - Reserves | D | 2-2 |