[12] Brest 1-0 St Etienne [20] 2021-12-01 18:00
Stadium: Stade Francis-Le Ble Round: 16
Referee: Mikael Lesage Home Manager: Michel Der Zakarian Away Manager: Claude Puel
Head to Head
| Frankrijk - Ligue 1 | 2021/04/24 11:00 | St Etienne v Brest | W | 1-2 |
| Frankrijk - Ligue 1 | 2020/11/21 16:00 | Brest v St Etienne | W | 4-1 |
| Frankrijk - Ligue 1 | 2020/02/16 16:00 | Brest v St Etienne | W | 3-2 |
| Frankrijk - Ligue 1 | 2019/08/18 13:00 | St Etienne v Brest | D | 1-1 |