[16] San Luis Quillota 0-0 Cobreloa [3] 2022-07-04 22:00
Stadium: Estadio Municipal Lucio Farina Fernandez Round: 18
Head to Head
| Chili - Primera B | 2022/02/16 23:30 | Cobreloa v San Luis Quillota | L | 2-1 |
| Chili - Primera B | 2021/10/01 23:00 | San Luis Quillota v Cobreloa | W | 1-0 |
| Chili - Primera B | 2021/05/30 16:00 | Cobreloa v San Luis Quillota | L | 1-0 |
| Chili - Primera B | 2020/11/12 14:00 | San Luis Quillota v Cobreloa | L | 0-1 |
| Chili - Primera B | 2020/10/12 15:00 | Cobreloa v San Luis Quillota | D | 0-0 |
| Chili - Primera B | 2019/08/12 00:00 | San Luis Quillota v Cobreloa | D | 1-1 |
| Chili - Primera B | 2019/04/14 20:00 | Cobreloa v San Luis Quillota | L | 3-0 |