| NCAAF | 09/26 19:00 | 1 | Southern v Mississippi Valley State | W | 38-25 | |
| NCAAF | 09/18 23:00 | 1 | McNeese State v Southern | L | 31-24 | |
| NCAAF | 09/11 23:00 | 1 | Southern v Miles Golden Bears | W | 41-24 | |
| NCAAF | 09/04 23:00 | 1 |
Southern
v
Troy
|
L | 3-55 | |
| NCAAF | 04/17 18:30 | 1 | Grambling v Southern | W | 7-49 | |
| NCAAF | 04/03 21:00 | 1 | Southern v Jackson State | W | 34-14 | |
| NCAAF | 03/21 00:30 | 1 | Southern v Texas Southern | W | 51-23 | |
| NCAAF | 03/06 19:30 | 1 |
Arkansas Pine Bluff
v
Southern
|
L | 33-30 | |
| NCAAF | 02/27 00:00 | 1 |
Southern
v
Alabama State
|
W | 24-21 | |
| NCAAF | 12/07 21:00 | 1 | Southern v Alcorn St | L | 24-39 | |
| NCAAF | 11/30 22:00 | 1 | Southern v Grambling | W | 30-28 | |
| NCAAF | 11/16 20:00 | 1 | Southern v Jackson State | W | 40-34 | |
| NCAAF | 11/09 22:00 | 1 | Southern v Lynchburg Dragons | W | 58-7 | |
| NCAAF | 11/02 21:00 | 1 |
Alabama A&M
v
Southern
|
W | 31-35 | |
| NCAAF | 10/26 19:00 | 1 | Southern v Alcorn St | L | 13-27 | |
| NCAAF | 10/19 19:00 | 1 | Southern v Texas Southern | W | 28-21 | |
| NCAAF | 10/12 23:00 | 1 | Prairie View A&M v Southern | W | 28-34 | |
| NCAAF | 09/28 23:00 | 1 |
Southern
v
Arkansas Pine Bluff
|
W | 31-7 | |
| NCAAF | 09/21 22:00 | 1 | Southern v Florida A&M | L | 21-27 | |
| NCAAF | 09/14 23:00 | 1 | Southern v Edward Waters Tigers | W | 61-0 | |
| NCAAF | 09/07 16:00 | 1 |
Southern
v
Memphis
|
L | 24-55 | |
| NCAAF | 08/31 23:00 | 1 | Southern v McNeese St | L | 28-34 | |
| NCAAF | 12/01 21:30 | 1 | Southern v Alcorn St | L | 28-37 | |
| NCAAF FCS | 11/24 22:00 | 1 | Grambling v Southern | W | 28-38 | |
| NCAAF FCS | 11/10 22:00 | 1 |
Arkansas Pine Bluff
v
Southern
|
W | 24-56 | |
| NCAAF | 10/27 23:00 | 1 | Southern v Jackson State | W | 41-7 | |
| NCAAF | 10/20 19:00 | 1 | Texas Southern Tigers v Southern | W | 7-21 | |
| NCAAF | 10/13 22:00 | 1 | Southern v Prairie View | W | 38-0 | |
| NCAAF | 09/29 23:00 | 1 | Alcorn St v Southern | L | 20-3 | |
| NCAAF | 09/22 21:00 | 1 |
Alabama A&M
v
Southern
|
W | 27-29 |